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Getting a detailed Physical - What blood testing should I ask for?

My work offers one of these half-day, spa-like setting full and thorough Physical.  They do all the routine stuff as well as some pretty detailed hearing chamber, eyesight testing, etc. etc. etc.  I'm going in next Friday morning (yes, I specificaly scheduled it on my OS rest day) and I will be fasting before I go in and they will be doing a blood test as well.

I know very little about blood tests.  Are they all the same, or are there specific things I should ask them to test for?  Hemoglobin levels?  Iron? Vitamin D?  Others?

Any of the smart medical or nutritional peeps have any advice on this?

Comments

  • at a minimum a CBC, cholesterol and PSA why you are at it is a urine check.
  • if it's your first physical in a while, just tell the doc what you do and he'll figure it out for you.

    Endurance sports can sometimes be connected to anemia. But, the standard stuff will cover that, hemoglobins, iron, etc.

    I'm pretty sure you'll get a baseline ECG, or at least make sure you do. You're very healthy (as far as I pick up from here), but we do stress our hearts all the time.

    I like the vitamin D test. My primary threw out some crazy numbers regarding how many of us are deficient and how it negatively affects us.

    And, I guess, you could try to get an exemption for testosterone therapy image
  • As I sit here practically 'whole-body fibrillating' after that 20/20/15 bike workout, I'll take a moment to answer this as an excuse to get more recovery time before I get on the treadmill.

    I agree with the suggestions above (CBC, Vit D, Cholesterol, Liver & Kidney, testosterone, PSA, thyroid, urine) and would like to add a couple more. I am big on the concept of recovery nutrition and one of the indicators that you're in a pro-inflammatory state is the level of your C-reactive protein. You put yourself through a lot training like this and if this is too high it is an indicator that you're not handling it all very well or that some other situation is dogging you. Another thing to think about is uric acid levels. Sometimes heavy duty workouts cause a lot of cell breakdown and knowing how well your body is handling the uric acid that derives from the breakdown of purines (parts of your DNA) is a good thing.

    I'll probably think of more while trying not to fall off the back of the mill...
  •  Cholesteral should be part of a "lipid panel". Equally important to cholesterol is checking LDL ("bad" cholesteral) and HDL ("good"cholesterol).  Exercise, although in most instances a huge help, is no garauntee that the LDL/HDL ratio is most favorable.

    Totally agree with checking Vitamin D levels: vitamin D has a big role in inflammation and pulmonary function. A deficiency is not unusual particularly for those that live in northern climates. 

  • EPO... Make sure Jess isn't spiking your Koolaid with PEDs. image
  • @Dino - that is TOO funny! He actually accused me of adding EPO to his turnips the other night when he crushed his bike w/o the next morning. And Joe M., if you happen to read this - yes, it's thanks to Gen we were eating roasted turnips! ;-)

    All - any thoughts on magnesium? Am I right that endurance athletes are at heightened risk for magnesium deficiency?

    Great input so far!
  • If you're eating right and getting plenty of veggies and protein you ought to be okay but I have to ask about the fuel you folks use during your workouts? Are you getting enough electrolytes during and after these workouts? The Mag level will most likely be in the standard blood test but ask to be sure.
  • Thanks for the feedback all. Keep them coming if you think of anything else.

    @Dino-- I've been rockin' the OS so sometimes I wander what Jess is slipping me.

    @Peter-- I have been off the "Recreational Sugar" and "Gluten Free" since Jan 2nd.I have been eating a tone of veggies and non-processed foods, so hopefully things are mostly good. I have been experimenting with something new this OS, Zero nutrition before or during any workout. I even went off plan one day and did a ~3hr Trail run after getting up and having nothing but water before and during and felt great. I almost always do a recovery shake and a ton of other stuff immediately after workouts. I also eat pretty much all day (snacking on fruit and nuts, etc.). I have not been hungry one single time since Jan 2nd and am down almost 8 lbs.

    My Cholesterol was ~280 with my HDL's very low the last time I had one of these. I went on Lipitor and it fell to like 150. I have not taken my Lipitor in at least 9 months so I am very curious to see if my new diet and as always extreme physical activity is enough to counteract my horrible genes. We'll see if I'll need to go back on the Lipitor.
  • Posted By Jess Withrow on 26 Jan 2013 04:05 PM

    @Dino - that is TOO funny! He actually accused me of adding EPO to his turnips the other night when he crushed his bike w/o the next morning. And Joe M., if you happen to read this - yes, it's thanks to Gen we were eating roasted turnips! ;-)



    All - any thoughts on magnesium? Am I right that endurance athletes are at heightened risk for magnesium deficiency?



    Great input so far!

    TOO FUNNY indeed!

    {Thread Drift Alert}

    Gen wants to know how you roasted them, and if they were any good.  We only have them raw...and *I* load them up with salt.  You can't have too much salt....  

     

  • @Joe - they were AWESOME roasted! I just peeled them, cut them into ~1 inch cubes, tossed them with a little olive oil, salt, and pepper, and roasted for 20-25' at 425, flipping them once. Great substitute for my go-to side of roasted redskin potatoes! If she REALLY wants to get crazy, tell her I riced some cauliflower yesterday...

    Back on topic... I am really interested to see what's happened with John's lipid panel. I'll be attributing any positive changes to his current gluten-free diet... ;-)
  • Hope I don't blow any fuses or offend anyone on the board (ie.. Medical docs), but blood tests done/evaluated by traditional medical route are really only designed to pick up big problems/pathologies. I work with people every day who have been feeling crappy for YEARS, and all along the way have been told "everything is normal" on their blood tests. This is because of two main reasons: 1. the lab ranges are determined via bell curves on a very unhealthy population, hence many fall within the lab ranges but actually HAVE metabolic dysfunction. 2. Medical doctors typically order VERY minimal tests. There are several reasons for this(this could be a whole other thread!),but testing for thyroid is the classic example.
    Most ALL medical doctors, endocrinologists included, only measure TSH and T4. But doctors who practice "functional medicine" like myself know that to really know IF and EXACTLY HOW the thyroid is dysfunctioning, a comprehensive thyroid panel is needed, which includes: TSH, total T4, FreeT4, total T3, free T3, TBG, FTI, T3 uptake, and probably most importantly(since most with hypothyroid in the U.S. have autoimmune thyroid/ "Hashimotos"), TPO and Tgb antibodies.
    Also, these and all other markers need to be evaluated within their "functional"range. What's that? Well TSH for example is usually 0.5 to 5.0 on a lab range (this is DIFFERENT from lab to lab and from year to year BTW!), but a functional range for TSH is 1.8 to 3.0, which you can see is a big difference. Suffice it to say that there are many people who fall within the lab ranges but are actually outside the functional ranges, which explains why they've been feeling sick for sooooo many years( some having even been told they're just crazy- ie... "Maybe we should start you on an antidepressant").
    Two last points. 1. TOTALLY agree with getting inflammatory markers measured. Inflammation is the REAL killer, and everyone should have CRP (c reactive protein) , and homocysteine measured. In fact, more recent studies have shown a much stronger correlation to elevated homocysteine and heart disease, than elevated cholesterol. But the medical model is slow to change ESPECIALLY when there is BILLIONS made in statin(cholesterol lowering) drugs every year ( BTW, did you know that studies have shown that those on statins have a 16X increase chance of developing peripheral neuropathy. This is because the statins deplete the cells of the enzyme CoQ10, which is needed to make ATP- which is ENERGY for the cells, and nerve cells are very highly metabolically and suffer the most ) 2. While everyone is "fat phobic" and thinks the lower the better with cholesterol and triglycerides, you don't want either of these TOO low. For example, you don't want cholesterol below 150: why? Well it's the building block of all our hormones, so if you don't think hormones are important, than go ahead and get your cholesterol real low. Also, triglycerides shouldn't be below 75 on a blood test: why? Well ALL the cells in your body have their protective cell walls made of fat.
    Sorry I went on so long, but this is a passion of mine, and I see people every day who have suffered for TOO long in a health care system that is THE BEST at crisis care, but leaves much to be desired with chronic health issues. The take home message: try and find someone who practices "functional medicine" and will do blood tests(and if warranted some speciality tests) that are more in depth, and just as importantly, will evaluate the results using the functional/optimal ranges.
  • Results are in... Oct  2010 was the last time I had this detailed exam done.  I had just started training for my first Ironman then and I was on 10mg per day of Lipitor.  I have not taken Lipitor in about a yr.  But I am now training for my 4th Ironman and have been on a Gluten Free diet for ~6 weeks and I have not eaten Recreational Sugar since Jan 2nd, 2013.  Anyways, here's the comparison of the simple things...   There are a bunch more line items but I didn't want to bore you all with everything.  

    Overall, I'm pretty damn proud of the results.  I don't know what most of the stuff means or if the "Reference" range they post is even what is supposed to be normal for a fit endurance athlete...  I'm shocked that my lipid profile is as good as it is with no meds.  I was ~280 on total cholesterol at my worst like 7 yrs ago and an LDL/HDL ratio was around 8. From my laymens look at it, my Testosterone and Free Testosterone levels seem on the low side.  The Hemoglobin and Hematocrit levels seem low as well, but I'm comparing to what I read in Tyler Hamilton's book, so maybe my sense of normal is warped...  Anyways, would love any feedback if anyone has any...



    13-Feb 10-Oct Units
    Age 37 34 yrs
    Weight 188 206 lbs
    BMI 24.9 27.2
    Body Fat % 10.5 not tested
    BP 110/72 108/76
    Resting HR 41 52 bpm
    Blood Test Results 13-Feb 10-Oct Reference Units
    Triglycerides 65 101 0-149 mg/dL
    Cholesterol, Total 195 206 100-199 mg/dL
    HDL 60 46 >39 mg/dL
    LDL 122 140 <130</td>
    mg/dL
    LDL/HDL 2.03 3.04
    VLDL 13 20 5-40 mg/dL
    C-Reactive Protein 0.33 - 0.00-3.00 mg/L
    Homocyst(e)ine, Plasma 9.2 - <11.4</td>
    umol/L
    Sodium, Serum 139 141 135-145 mmol/L
    Potassium, Serum 5.1 3.9 3.5-5.2 mmol/L
    Chloride, Serum 99 102 97-108 mmol/L
    Glucose, Serum 93 93 65-99 mg/dL
    Calcium, Serum 10 9.4 8.7-10.2 mg/dL
    Phosphorus, Serum 3.5 3 2.5-4.5 mg/dL
    BUN 20 18 5-26 mg/dL
    Creatinine, Serum 0.96 1.01 0.76-1.27 mg/dL
    BUN/Creatinine Ratio 21 18 8-27
    Uric Acid, Serum 4.2 5.5 2.4-8.2 mg/dL
    Iron, Serum 141 117 40-155 ug/dL
    Iron Bind.Cap.(TIBC) 318 293 250-450 ug/dL
    Iron Saturation 44 40 15-55 %
    TSH 2.37 1.97 0.450-4.500 uIU/mL
    T4, Free(Direct) 1.09 0.82-1.77 ng/dL
    TPO Ab 7 0-34 IU/mL
    Hemoglobin 13.7 14.1 >=13.9 and <=17.1</td>
    g/dL
    Hematocrit 41.3 41.3 >=42.0 and <=54.0</td>
    %
    RBC 4.66 4.61 4.10-5.60 x10E6/uL
    WBC 3.8 5.6 4.0-10.5 x10E3/uL
    Platelets 197 200 140-415 x10E3/uL
    Testosterone, Serum 421 348-1197 ng/dL
    Free Testosterone (Direct) 7.6 8.7-25.1 pg/mL
    Magnesium, Serum 2.1 1.6-2.6 mg/dL
    Vitamin D, 25-Hydroxy 56.5 37.2 32.0-100.0 ng/mL


  • John! Work Works, huh? Looks like exercise beats Lipitor hands down. As far as testosterone: I am a little surprised the Free Testosterone is low. I was expecting low Total Testosterone and low-normal Free Testosterone. You got the opposite. I bet Rich wrote a transition week or 2 into your program after the OS. Be sure to do that so you are fresh and ready for the work you need to do this summer. Good work.
  • @John - I recently got my T tested as part of some blood work. My Free T was 12 which is a normal range but not optimal. My Doc said the reported interval ranges reported on blood test represent "normal" and not necessarily optimal or healthy. If most folks are low vitamin D, for example, then one's low D measure may fall within the "normal" simple because that is where most folks fall. I believe normal is much different than optimal. Your Free T seems low to me, but all things are relative and everyone is a unique n=1.
  • @Steve, I couldn't agree with you more. The number of people with so called "normal" markers that are living in a diseased state is sad. The further you delve into it all it's pretty far from objective science. 

    @John, markers all look pretty good, but know that you live in a world where the difference between ordinary and extraordinary are a very fine line and the test you just did is not specific enough (why I haven't had a blood test in some time). I would look further into looking at your Testosterone and GH production or even consider supplementing naturally to see how you feel, especially as you approach 40. In the end I'd be proud of your results.

  • I've been looking at incorporating tests from InsideTracker into my practice. They take ranges based on research for the type of person and athlete you are vs. general public. One of my pro teams used them. I was impressed with the results.
  • John- very good results, you should be proud of taking control of your health. Only a few comments:

    Triglycerides- they are a little low (functional range 75-100). I would take a good quality Omega 3 supplement and make sure getting good fats in diet (avacados, fish, coconut oil, etc..)

    Homocysteine- little high (functional range <7.5). Increased levels of "methyl donners" (Vit. B12) will decrease this</p>

    WBC's- little low (functional range 5-8). This most likely due to general immune suppression associated with heavy training (ie.. be careful about overtraining). 

     

    There were a few other things a little outside of the functional ranges, but taken as a whole, these were the only I felt to comment on. Also, all iron levels were very good, which can sometimes be a problem with endurance athletes. Again, great job!!

  • @Steve--
    Many thanks for taking a look! on your comments:

    Triglycerides- mine have always been way high, so I was actually happy they were low. I didn't realize they could be too low... I take Omega 3 supplements every day and eat a lot of Salmon, Avacado, etc.

    Homocysteine- I already take a Super B-Complex supplement...

    WBC's- You're too late... I'm just getting over a cold that lasted about 2.5 weeks and caused me to stand down from training in a very major way.
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