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Quitting my Statin drug today

Last week I had my annual physical and my PCP could find no reason that I'm tired all the time and have a very hard time getting back into my training program since an injury last summer.  I've gained weight (from 150 race weight to 167 now) and lost significant fitness measured by FTP and 5K time.  The doc is not concerned, says he thought I was too thin before and I'm still his most fit patient in my age range (about to turn 53).  Things are definitely moving in the wrong direction for me, however, and faster than normal aging would predict.  So, after a lot of research, against medical advice, I'm going to try two months without my 5mg of Crestor and take a combination of fish oil and niacin and commit myself to six days a week without any processed sugar, and stick to a fishy semi-paleo diet.  We'll see if my LDL shoots back up and, more importantly, if my ability to get out of bed and hit the road improves.

Anybody else out there made a connection between a statin and diminished energy for training?  Suggestions for risk assessment if I decide to live with a higher LDL number in order to keep my energy for exercise?  I have taken CO-Q10 without noticeable improvement.

Comments

  • I can't advise you on whether or not to use the statins - that's between you and your MD, with whom you should discuss this even if you end up going against his advice. But in regards to your other question about fatigue and statins, you may want to read this from the NY Times.  Final quote "“Statins are anti-aging for arteries,” he says. “If you take them, you’ll have younger arteries. Unfortunately,” he adds, “they are not anti-aging for muscles.”"

    I hope that your combination of renewed exercise and detailed attention to diet will do the trick for your cholesterol, so you can avoid these nasty drugs. I'm one of those MDs who thinks prescription drugs can sometimes (?often) cause more problems than they solve. In this case, you are weighing the positive benefits of getting suffiecient exercise against the potential positive of lower LDL. I doubt there is one right answer to that question.

  • No advice here, but the timing is interesting, as my dad is going through basically the same experiment, for similar reasons, starting a week ago. Very interested to hear about your results!
  • @Al: Thanks. I saw that NYT article. I couldn't seem to find the study online that supports the article. My father was a pathologist who described himself as a therapeutic nihilist--he really didn't like to disturb natural processes with drugs. He used statins, however, to lower his LDL. I find myself wishing he were still around to talk about this with. After all my research, I'm wondering if there's a possibility that the statin drugs he took triggered the pulmonary fibrosis that killed him. Idiopathic, all his docs said, ironic for a pathologist. I appreciate having you on the forum.

    @Mike, thanks for the comments. I haven't been very active on the forums in a while, but I'll try to give regular progress reports. Please let me know how it goes for your dad.
  •  Today is the fourth day of my statin-free status, and here's what I noticed:  I slept the whole night last night for the first time in a long time.  After seven hours, I woke up ready to go.  Did a 5K run test that told me I'm back where I was about a year before my injury last summer, so it leaves lots of room for an impressive come-back.  It was the first time I ever felt I executed the test accurately.  Increased my effort steadily for almost even splits, had very little kick at the end.  My 5K indicator on the GPS went off a second before everything went black.  Yep, that's as fast as I can go today.

    Definitely have more energy today after recovering from the 5K run test a couple of hours later.  If I can sleep through the night regularly, that's going to weigh heavily in my decision-making process.

  •  Important lesson learned today:  remember to take the niacin after the workout, not before.  The time-release mechanism gets all whacky when I get my heart rate high.  A few minutes after finishing my bicycle intervals, the time-release niacin all went off at the same time like a whole pack of firecrackers.  Burning sensation and my whole body turned red as if I were freshly sunburned.  It goes away in less than an hour, but it's uncomfortable enough to remind me not to do that again.

  • Good to know. How's the energy and sleep going?
  •  I'm definitely sleeping better, so I feel more refreshed in the mornings.  It's just easier to get out of bed and hit the road, no doubt.  It's hard to isolate the effect of going off the statin because I have also exercised more vigilance with my diet--no processed sugar and no alcohol.  Also, the weather has been great and that always helps, getting off the trainer and outside.

  • I am following this thread and am really interested in results.

    My DH has been on a statin for years. With input from me, he has slowly but steadily increased veggies and decreased red meat. His numbers have improved and I feel like he can get off the statin as long as he continues this way. His doc is reluctant, despite the excellent numbers on lowest possible dose (1/2 tab of lowest tab available). But DH has hard time with muscle fatigue, elevated CKs, and trouble sleeping.

    I am gently urging and he is at the point of agreement because he really wants to lose more weight, and at this point, increasing exercise intensity and/or duration is his only option. (he is an MD himself, and I am an NP)

    When we go live, I will let you know.
  • For anyone interested, I've been off my statin now for three years and I haven't had a heart attack yet. My LDL runs high, even when I eat well, but my blood tests for inflammation measure very, very, low. When I went off the statin and made the commitment to eat better, I have kept that commitment unevenly over the past three years, but my weight has stayed at or below 150. I'm training for IMLP end of July and on schedule to be under 140 for race day. It's hard to draw any conclusions when n=1 and I'm only 56 years old, but so far, so good. By the time he was my age, my paternal grandfather had been dead for three years. My father was diagnosed with idiopathic pulmonary fibrosis when he was 56, and lived another 11 years fighting for every breath. I won't set any triathlon records this year, but if I complete my first full ironman, I'll feel like my experiment is paying off.
  • I took lipitor for 3 year when I was overweight. I lost 80 pounds and got off it 3-4 years ago. I didn't really notice any changes, but it was nice to be free of daily medication....
  • Neill, thanks for following up with this thread, and good luck at IMLP!
  • Great! (Especially the inflammation markers) I look forward to being there @ LP when you motor thru that IM distance for the first time.

  • I took Lipitor from ages 27-37... I went to a gluten "light" diet and and my lipid profile came right into line and has been fine ever since. Nice to not be on the drug anymore...
  • Good for you! My husband left lipitor behind a couple years ago.

  • I noticed an arrhythmia a few months ago just after turning 58, and began seeing a cardiologist. I had cut back on simvistatin to about 50% of evenings on my own. Well apparently my genetics require that I maintain the nightly protocol. If you are over 50 I recommend paying the $80 as I did for a CT Calcium Score image. My score is 607 (fairly high) and the CT clearly shows the white calcium on my heart. Thankfully my echo and NM SPECT stress test show my heart is "normal" but I can no longer train by HR since it tends to range from 20-35 bpm higher at Z2-3.
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